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Sharba Bandyopadhyay

About


Current Position: Assistant Professor and Wellcome Trust DBT Fellow, Department of Electronics and
Electrical Communication Engineering, Indian Institute of Technology Kharagpur (since 19th March 2014).


National Brain Research Centre – Manesar, HR, India
Wellcome Trust DBT Fellow, Dates: July 2012- March 2014.


University of Maryland - College Park, MD
Assistant Research Scientist (Research Track Faculty), Institute for Systems Research and Department of
Biology, Dates: July 2009- June 2012. 

Research Statement


Our brain enables the processing of various sensory information around us, thus facilitating effortless interaction with our environment. The brain is unparalleled in its computational abilities to process sensory information in an adaptive manner. Many real-life problems to do with pattern recognition and learning in single or multiple sensory space(s) are solved or learned by the brain easily whereas artificial algorithms struggle to successfully perform even simple behaviors. Our objective is to find the underlying principles by which the brain solves such problems. Specifically, in terms of structure of cortical circuits: since precise nature of connectivity between specific types of neurons in a network determines its function - we ask what is the precise connectivity of neurons of different types (example: excitatory and inhibitory) that form local functional sensory micro-circuits or modules in the cortex; and, in terms of adaptation/learning by such circuits: how does the connectivity of such circuits change over time, at rapid or long (developmental) time scales, depending on cognitive demands or experience. Our research will not only enhance artificial computation but also allow us to understand the specific deficits underlying various learning and developmental disorders (like dyslexia and autism spectrum disorder). We use a variety of techniques to answer questions: 1) In vivo electrophysiology (single and multiple electrodes) 2) Neuroanatomical methods using retrograde and anterograde labeling and viral techniques 3) In vivo and in vitro Ca2+ Imaging 4) Mapping micro-circuitry with optical stimulation 5) Computational Modeling of Neural Computation.

Research

  • 1 Neuroscience
  • 2 Computational Neuroscience
  • 3 Physiological & Cognitive Data Analysis

Publications

  • Das P., Ganguly S. , Maity P. P., Sristava H. K., Bose M. , Dhara S. , Bandyopadhyay S. , Das A. K., Banerjee S. , Das N. C., Converting waste Allium sativum peel to nitrogen and sulphur co-doped photoluminescence carbon dots for solar conversion, cell labeling, and photobleaching diligences: A path from discarded waste to value-added products, Journal of Photochemistry and Photobiology B: Biology, 2019
  • Datta P. K., Pradeep N. D., Venkatesh Y. , Srivastava H. K., Bhattacharya S. , Mehra M. , Bandyopadhyay S., One and Two-Photon Uncaging: Carbazole containing inbuilt o-HydroxycinnamatePhotoremovable Protecting Group for Dual (Similar or Different) Release of Alcohols with Real-Time Monitoring, Organic letters, 20, 2241-2244, 2018
  • Muralidharan S., Dirda N. D., Katz E. J., Tang C. M., Bandyopadhyay S. , Kanold P. O., Kao J. P., Ncm, a Photolabile Group for Preparation of Caged Molecules: Synthesis and Biological Application, PLOS One, 11, 2016
  • Winkowski, D.E.*, Bandyopadhyay, S.*, Shamma, S.A., Kanold, P.O., Frontal cortex activation causes rapid plasticity of auditory cortical processing (*equal contribution), Journal of Neuroscience, 33, 18134-18148, 2016
  • Bandyopadhyay, S. and Young E.D., Nonlinear temporal receptive fields of neurons in the dorsal cochlear nucleus, Journal of Neurophysiology, 110, 2414-2425, 2013
  • Viswanathan, S., Bandyopadhyay, S., Kao, J.Y., Kanold P.O, Changing microcircuits in the subplate of the neonatal cortex, Journal of Neuroscience, 32, 589-601, 2012
  • Bandyopadhyay, S., Shamma, S.A. and Kanold P.O., Dichotomy of functional organization in the mouse auditory cortex, Nature Neuroscience, 13, 2010
  • Bandyopadhyay, S., Reiss, L.A.J. and Young, E.D, A receptive field for dorsal cochlear nucleus neurons at multiple sound levels, Journal of Neurophysiology, 98, 3505 - 3515, 2007
  • Khan, S., Bandyopadhyay, S., Ganguly, A.R., Saigal, S., Erickson III, D.J., Protopopescu, V. and Ostrouchov, G, Evaluation of different mutual information estimation measures in short and noisy time series, Physical Review E, 76, 2007
  • Reiss, L.A.J., Bandyopadhyay, S. and Young, E.D., Spectral contrast and nonlinearity in the dorsal cochlear nucleus neurons, Journal of Neurophysiology, 98, 2133-2143, 2007
  • Khan, S., Ganguly, A.R., Bandyopadhyay, S., Saigal, S., Erickson III, D.J., Protopopescu, V. and Ostrouchov, G., Nonlinear statistics reveals stronger ties between ENSO and the tropical hydrological cycle, Geophysical Research Letters, 33, 2006
  • Bandyopadhyay, S. and Young E.D., Discrimination of voiced stop consonants based onuditory nerve discharges, Journal of Neuroscience, 24, 531-541, 2004

Projects

  • NIR-Light Responsive Systems: Single and Dual (Simultaneous and Sequential) Release of Anticancer Drugs, Client: Science and Engineering Research Board (SERB), Co-P.I.: Sharba Bandyopadhyay, Completed
  • Institute Small Animal House, Client: IIT KHARAGPUR, Co-P.I.: Sharba Bandyopadhyay, Completed
  • Understanding Vocalization Development Deficits in Mouse Models of Autism Spectrum Disorders-Role of Subplate Neurons (SGIGC-2015), Client: IIT KHARAGPUR, P.I.: Sharba Bandyopadhyay, Completed
  • Audio visual integration and learning - implications for dyslexia, Client: MHRD, P.I.: Sharba Bandyopadhyay, Completed

Awards

  • Wellcome Trust DBT India Alliance Intermediate Fellowship - Year:
  • Ramalingaswami Fellowship awarded from DBT Government of India - Year:
  • Johns Hopkins University Fellowship - Year:
  • Encouragement Award from Jagadish Bose National Science Talent Search - Year: 1996
  • National Level Award from Indian Association of Physics Teachers - Year: 1995

Research Group

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Abhrajyoti Chakrabarti
Ph. D.
Research Scholars
Auditory Neurophysiology
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Adarsh Mukesh
Ph. D.
Research Scholars
Auditory Neurophysiology
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Hemant Kumar Srivastava
Ph. D.
Research Scholars
Neurobiology
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Madhur Parashar
Ph. D.
Research Scholars
Neurobiology
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Miyangshu De
Ph. D.
Research Scholars
Neurobiology
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Muneshwar -
Ph. D.
Research Scholars
Neuro Physiology
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Sudha Sharma
Ph. D.
Research Scholars
Neurophysiology
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Suman Kumar Gunin
Ph. D.
Research Scholars
Neurobiology
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Swapna Agarwalla
Ph. D.
Research Scholars
Auditory Neurophysiology
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Yuvarani M S
Ph. D.
Research Scholars
Neurobiology